This research aims to review impacts of the utilization of natural resources and climate change in Sudan. The utilization of natural resources brought power to the Sudanese State; however, produced patterns of disparate development that initiated social unrest, environmental degradation, and armed conflicts powered by the concept of center-periphery. They formed also, external threats to the Sudanese State whereby initiating foreign integrated strategies to weaken Sudan to benefit from its richness of natural resources. Americas theory of creative chaos has been operating in Darfur since 2003, and beforethat the Israelis role in secession of Southern Sudan. The Nile River became a source of political tensions between Sudan and its neighbors. Climate changes in Sudan caused deterioration of millions of hectares of arable land and fertile soils; loss of biodiversity; changes; scarcity of tree products; deterioration of Gum Arabic production; general deterioration in the natural production base and in the renewal of natural resources; deterioration in the irrigation systems; and the expansion of the deserts environment. Sudan needs national plans to suppress impacts of the utilization of natural resources and climate change through effective national plans and effective membership in the international action systems combating climate change.