For physicians of all nations, the rich spiritual heritage of the great Abu Ali ibn Sino is priceless to this day: issues of the relationship between morality and science, upbringing and education, social responsibility, the formation of a highly moral personality. The thoughts expressed in his works, the description of the symptoms of diseases and methods of their treatment do not lose their significance. On the contrary, many of the methods and procedures offered by modern medicine were presented in a simple and understandable language in the medical works of the scientist. ... The relevance of studying the legacy of Avicenna using modern experimental and laboratory research methods in order to develop new alternative approaches to the tactics of diabetes mellitus therapy is beyond doubt. The aim of this study was to study and objectively analyze the problem of diabetes mellitus in the invaluable work "Canon of Medicine" in the light of the modern development of diabetologcy.