This study investigates the impact of soil radioactivity levels on cancer risk in the Atbara region.Through relative risk analysis, the calculated relative risk (RR) values for each sample were determined, providing insights into the potential cancer risk associated with radiation exposure. The results indicate that while detectable levels of radioactivity were found in the soil samples, they remain below international safety thresholds. This study contributes to our understanding of environmental radioactivity in the Atbara region and underscores the importance of continued monitoring to ensure the health and safety of the local population.