The study explored the relationship between leadership practices of school heads and trust in management of teachers in public secondary schools of Panabo City Division. Also, it investigated the association of the involved variables and the domains of leadership practices of school heads that significantly influence trust in management of teachers. With the use of probability sampling, 166 public secondary teachers were selected as the respondents. Utilizing the descriptive-correlational survey method, the data collated were analyzed through the use of Mean, Product-Moment correlation and Regression Analysis. Results revealed that there was a high leadership practices of school heads and a high trust in management of teachers among the respondents. Furthermore, there was a significant relationship between the leadership practices of school heads and trust in management of teachers. Moreover, all domains of leadership practices of school heads, namely, leading strategically, managing school operations and resources, focusing on teaching and learning, developing self and others, and building connections, were found to have significantly influence the trust in management of teachers. Based on the findings, it was further suggested that higher officials in the Department of Education may identify means on how to strengthen the leadership practices of school heads which would boost trust in management of teachers. More so, future researchers may further explore the involved variables considering other factors and research methods.