This study aimed to determine the significance of the relationship between the leadership practices of school heads and school organizational health in the Division of Panabo City. Using a descriptive correlational research design, the study involved thirty (30) school heads selected through purposive sampling. Validated survey instruments were employed to gather data, which were analyzed using weighted mean, Pearson product-moment correlation, and multiple regression analysis. Results revealed that both the leadership practices of school heads and the level of school organizational health were at an extensive level. A statistically significant positive relationship was found between the leadership practices of school heads and school organizational health. Furthermore, multiple regression analysis showed that all six domains of leadership practices, vision, mission, and goals; teaching and learning; managing organizational systems and safety; collaborating with families and stakeholders; ethics and integrity; and the education system, significantly influenced school organizational health (p < .05). Among these, managing organizational systems and safety registered the highest influence. The coefficient of determination (R² = 0.650) indicated that 65% of the variance in school organizational health could be explained by the leadership practices of school heads. The findings support transformational, social learning, and adult learning theories.