The aim of this study was to use exploratory factor analysis to investigate the impact of consumption of various drugs (smokeless tobacco as known as Tabu in Somalia, Tramadol, and cannabis) on students’ academic achievement in light of the students’ lack of discipline, poor communication skills, participation in-class activities, and GPA at secondary schools in Mogadishu, Somalia. This study applied factor analysis to advanced quantitative research methods. This study also concentrated on target respondents 266 and featured teaching and non-teaching staff who work in public and private schools. To collect and analyze the data, a questionnaire and SPSS Version 20 were used. Cronbach’s Alpha The.908 indicated that the data’s dependability was correct. The correlation of the variables in this article was (r =.865*). The KMO value of the data .869 appears to be convenient for factor analysis in terms of sample size. Also, Barlett’s Test is found to be scientifically significant. Factor analysis The performed scree plot curve, the total variance explained, rotated components matrix, and anti-image values varied from 0.859 to 0.844. The main findings show that drug misuse, including cannabis, tramadol, and smokeless tobacco, has a negative effect on a student’s academic achievement in terms of conduct, poor communication, participation in-class activities, and GPA in secondary schools in Mogadishu. We recommend the government of Somalia cracks down on traffickers who bring smokeless tobacco and other drugs that harm Somali students and produce rules that protect them against drug abuse. We also recommend that the Somali community, particularly teachers, school principals, and religious leaders, raise awareness about how to prevent and treat drug abuse, particularly with tabu and tramadol.