The growth of E-commerce enables women entrepreneurs to generate new ideas and work by setting their own schedule. It is pertinent to make a microscopic analysis of the available opportunities and constraints in E-commerce for women entrepreneurs. Hence an attempt is made in this paper to examine the various challenges faced by women entrepreneurs who use online platforms to start, grow and sustain their business and enlighten them are the availability of more opportunities to encourage them to make a diffuse of online platform to reap in rich harvest in their vision. The entire world is witnessing a marvelous evolution in electronic commerce, and India is no exception. Women have made significant contributions to these evolutions, and those contributions have shifted to empowerment. E-commerce trading and marketing of goods and services through the internet additionally referred to as electronic commerce. Since the early 2000s, when India sought wide spread access to a secure online transaction system, the countrys E-commerce sector has expanded dramatically.