The economic development has changed the scenario of social and cultural environment within the country specially, for women. Studies also prove that rural sector women have engaged in small-scale entrepreneurship programme and turned as successful entrepreneurs. Government programmes for women entrepreneurship development associated with banks financial support and the Self-help Groups moment made women to turn as entrepreneurs. However there are several challenges to empower women as entrepreneurs. Still they have challenges which are case specific region specific in nature. This paper attempts to analyse such challenges of women entrepreneurs in Uttara Kannada district of Karnataka state. The main objective of the study is to identify the challenges associated with empowerment of women entrepreneurs. This paper is descriptive in nature and the analysis is based on secondary data and information collected from published articles, case studies, internet sources and review papers. Studies gives insights into main challenges faced by women entrepreneurs. The study posits the financial support by banks helps the women entrepreneurs to increase their income and support for economic development of the country by creating job opportunities. It is been found that government support, funding family support and technical knowledge are considered helpful to overcome these challenges.