Green Human Resource Management (GHRM) has been an important practice that is being applied by many organizations in their bid to reduce environmental impact as well as ensure an improved long term business performance. This research aims to establish the correlation between GHRM and organizational performance, while adopting pharmaceutical organizations. Pursuing sustainable environmental practices to the HR operative functions of the business in industry 5.0 perspective of sustainable goal achievement. This paper reveals how GHRM directs a focus on sustainability, optimises business performance and also improves organisational image so as to create organisational success. Keeping this in view the study through a light on theoretical and conceptual considerations of GHRM practices and the strategic implication of these practices for the pharmaceutical industry. The recommendations acquired are expected to be beneficial for both the HR specialists and organizations, as well as the policymakers and entrepreneurs who are interested in the integration of sustainability strategy with organizational goals.