Study This aim For analyze role environment work and culture organization to performance employee with satisfaction Work as intervening variable : Employee performance is factor crucial in reach objective optimal organization . Environment conducive work and culture strong organization allegedly can increase performance employee through improvement satisfaction work . The research method used is quantitative with Structural Equation Modeling - Partial Least Square (SEM-PLS) approach . Research sample consists of of 98 selected respondents use purposive sampling technique . Instrument study in the form of questionnaire that has been tested validity and reliability . Data analysis was carried out using SmartPLS software For testing structural models and testing hypothesis . Research results show that environment Work influential positive and significant to satisfaction Work employees . Culture organization is also proven influential positive and significant to satisfaction work . Satisfaction Work as intervening variables have influence positive and significant to performance employees . Findings This indicates that satisfaction Work play a role as a mediator in connection between environment work and culture organization to performance employees . Implications practical from study This is importance management in create environment comfortable and constructive work culture positive organization For increase satisfaction and performance employee in a way sustainable .