China and Uzbekistan are both part of the ancient civilization of the Silk Road, and both countries have rich deposits in history, culture and sports tourism resources. In the new era, China and Uzbekistan are supposed to engage in constructive sports cultural exchanges and cooperation on the basis of the Belt and Road Initiative, exploring the potential of sports tourism cooperation and opening up new fields of economic cooperation actively. More significantly, China and Uzbekistan should take the development of sports tourism industry as a breakthrough to cultivate new points of growth in their own economies, thus enhancing the comprehensive level of sports cultural exchange and economic cooperation, and ultimately becoming the epitome of international cooperation in sports tourism for the countries along the Belt and Road. In this process, the exchanges and collisions of different cultures fully practiced, the theory of people-to-people and industry-to-industry sufficiently interpreted, the Belt and Road has provided a long-lasting driving force for the benefit of the people of all countries.