The research adopted the Unified Theory of Acceptance and Use of Technology (UTAUT) and Hofstede's Cultural Dimensions Theory to determine how performance expectancy, effort expectancy, social influence, and facilitating conditions and two moderators (uncertainty-avoidance and individualism-collectivism) interact and affect the adoption of Smart Lockers for last-mile delivery. A sample of 796 was collated from international students in twenty universities in eleven Provinces in China. The outcome of the Structural Equation Model analysis (SmartPLS version 4) indicates that performance expectancy, effort expectancy, social influence, and facilitating conditions positively affect the adoption of Smart Lockers for last-mile delivery. In addition, uncertainty-avoidance and individualism-collectivism did not moderate the associations between UTAUT dimensions and the adoption of Smart Lockers. Finally, the study adds to the literature on combining the UTAUT model and Hofstede's cultural dimensions, enriching theoretical studies on technology adoption and providing logistic delivery companies insight into understanding users' behaviors.