Quality management is a critical area in the intensification of global market competition. Determinants of quality performance of Indian industry managers are to be evaluated. Information was collected using a designed questionnaire based on four critical success factors from 342 respondents from different manufacturing industries in Southern India using Google Forms. Statistical tests, such as correlation, regression, and analysis of variance (ANOVA), are employed for results validation. Customer Focus, Continuous Improvement, Employee Involvement, and Feedback & Measurement independent variables are measured, and their impacts on quality performance are examined. It is confirmed that these factors combined explain 89.20% of quality performance variance and leave 10.80% to other unspecified factors. The study provides insight into Total Quality Management in the manufacturing units and sheds light on effective excellence management performance. It is confirmed that Indian industries can utilise these insights to enhance their excellent management performance and overall effectiveness. The study confirms the TQM enactment nexus in the Indian manufacturing sector, which is a valuable framework for industry practitioners and policymakers.