This study examined the influence of Information and Communication Technology (ICT) infrastructure strategy on the performance of private universities in Kenya. The study was guided by strategic management theories, particularly the Resource-Based View (RBV), which posits that digital capabilities constitute strategic resources that can enhance organizational performance. A descriptive and explanatory research design was adopted, targeting faculty, administrative, and ICT support staff in private universities. Stratified random sampling was employed, yielding 237 valid responses. Data were collected using a structured Likert-scale questionnaire and analyzed using SPSS. Binary logistic regression analysis revealed that ICT infrastructure strategy had a strong, positive, and significant influence on university performance (B = 3.135, Wald = 61.753, p < .001). The model demonstrated substantial explanatory power (Nagelkerke R² = .677) and high predictive accuracy (92.4% overall classification accuracy). The odds ratio (Exp(B) = 22.995) indicates that a one-unit increase in ICT infrastructure strategy increases the likelihood of high university performance by approximately 23 times. The study concludes that robust ICT infrastructure such as high-speed internet connectivity, digital resources, and reliable online platforms significantly enhances academic, operational, and financial performance. The study recommends sustained and strategic investment in ICT infrastructure to strengthen digital delivery, research productivity, and administrative efficiency in private universities in Kenya.