Agriculture sector is one of the primary sectors of the Indian economy. The agriculture sector contributes 19.9 percent of the GDP for the year 2020-21 as compared to 17.8 percent of the GDP for the year 2019-2020. The present research study is related to the manpower management in the agro based enterprises. An attempt is made to study and to identify the functional areas of human resource management and its practises employed in the agro based enterprises during COVID19 pandemic. The present research study is restricted to the Nanded city of Maharashtra state. It is observed that lockdown and social distancing has played significant role in the human resource management practices of agro based business. Even though the agriculture sector was given the status of emergency services and has been excluded from the lockdown and agriculture market was not closed but avoidance of social gathering restricted the agro based enterprises to some extent. It is found that the human resource management practices have been changed as per the guidelines of Government from time to time. It is concluded that there is an impact of COVID19 pandemic on human resource management practices in Agro based enterprises of Nanded city as specific location and in general to all sectors of the economy in the nation. It is concluded that procurement related strategies of small agro based enterprises in Nanded city are slightly changed for the safety of employees. It is suggested that the entrepreneurs of small agro based enterprises should give the facility of work from home to the employees wherever possible. The employee productivity and work culture should be properly managed by the agro based enterprises in Nanded city.