The main objective of this study was to verify the moderating role of Information Technology on the relationship between KM implementation and organizational performance in a university context through Abdelmalek Essaadi University. by collecting the views of teacher-researchers, using a hypothetical-deductive reasoning approach and a quantitative working method. Our questionnaire was administered to a representative sample of 88 teacher-researchers from the different institutions of the university under study. The results obtained using Hierarchical regression prove the moderating and positive role of Information technology on the intensity of the relationship between the application of the KM and (Training, research, publication, and governance) as indicators of organizational performance with a change in the correlation rate from R=0.917 to R=0.974 with the addition of leadership as a moderator variable with a degree of impact of 5.7%. This paper presents empirical evidence on the importance of the organizational, technical, and human factors on knowledge management implementation and enhancing performance.