The purpose of the study is to develop scientific, methodological and practical recommendations for the development of human capital management mechanisms for high-tech industrial enterprises in the digital economy, contributing to the rationalization of staff employment, creating favorable conditions for their innovative development and providing growth economic efficiency of economic activity of industrial enterprises. The object of the study is the human capital management system high-tech industrial enterprises, introducing digital technologies, focused on their innovative development. The subject of the study is the system of organizational and economic relations arising in process human capital management of high-tech enterprises implementing digital technologies, in the interests of their innovative development.