Currently, the universe is experiencing a rapid systemic modification in the disease patterns resulting in a sharp increase in the non-infectious diseases and a marked drop in infectious diseases. Central obesity, hyperglycemia, hypertension, and hyperlipidemia are the diseases included in metabolic syndrome. Herbal medicines may be considered effective agents for the treatment of metabolic syndrome since these plants consist of various bioactive compounds with a synergistic effect when compared with the monotherapy of chemical agents. These complex diseases in metabolic syndrome can be managed by treatment or prophylactic therapy with these bioactive compounds. Therefore, the present study reviews various medicinal plants beneficial effects in treating diabetes mellitus, which is one among the metabolic syndromes.