Groundnut is one of the most important oilseed crop cultivated widely through the tropic and warm temperate regions. The Sclerotium rolfsii is the most dangerous soil borne pathogen and cause damages of stem and pod rot mostly. The effect of botanicals on inhibition of colony growth and germination of sclerotia of different stages was significant. Among all botanicals, Neem proved superior and recorded maximum inhibition at 3% concentration (39.17%) and 4% concentration (44.25%) followed by Garlic crude extract at -3% concentration (33.09%) and 4% concentration (39.14%), Pungam oil, Calotrophis leaf e-xtract and finally Lemon grass leaf extract. Neem oil inhibited germination of sclerotium on 7th day after inoculation (44.25%). All stages of sclerotia were inhibited to the maximum at higher concentration of Neem (Immature, partial, mature). Minimum growth period was recorded in Calotrophis treatment, where 7 day, 13 days and 16 days for immature, partial mature and mature stages of sclerotia respectively.