stdClass Object
(
    [id] => 11841
    [paper_index] => 202311-01-015052
    [title] => DYNAMICS OF MICROCIRCULATORY CHANGES IN THE RETINA OF PATIENTS WITH CHRONIC KIDNEY DISEASE AFTER KIDNEY TRANSPLANTATION
    [description] => 
    [author] => Umida F. Mavlyanova, Azamat F. Yusupov
    [googlescholar] => https://scholar.google.co.in/scholar?cluster=17330541460839580147&hl=en&as_sdt=0,5
    [doi] =>  https://doi.org/10.36713/epra15052
    [year] => 2023
    [month] => December
    [volume] => 9
    [issue] => 12
    [file] => 1000pm_5.EPRA JOURNALS 15052.pdf
    [abstract] => Objective: This study aimed to assess microvascular changes in the retina over time in patients with chronic kidney disease (CKD) following kidney transplantation.
Methods: A total sample of 54 CKD patients (108 eyes) was prospectively observed for 2 years to evaluate the dynamics of microvascular parameters. Two study groups were formed: Group 1 comprised 36 patients (72 eyes) who underwent kidney transplantation, and Group 2 comprised 18 patients (36 eyes) receiving hemodialysis and conservative treatment. Patients were examined before the operation, within 2 months post-operation (early postoperative period), and at 12 months post-operation (late postoperative period).
Results: Optical coherence tomography angiography (OCTA) results demonstrated that retinal parameters, including area, perimeter, and circularity index of the foveal avascular zone (FAZ), showed recovery over the 12-month observation period after kidney transplantation, indicating a positive trend in the macular region. Similar trends were observed for overall vessel density, perfusion, and choroidal vascularity index (CVI) parameters. Statistical analysis revealed significant differences (p<0.05) between the groups in terms of FAZ area and CVI.
Conclusion: The primary microvascular changes in the retinas of patients with end-stage CKD involve reduced vessel density and perfusion volume in the superficial capillary layer.

    [keywords] => chronic kidney disease; kidney transplantation; microvascular changes; optical coherence tomography angiography (OCT-A).
    [doj] => 2023-12-05
    [hit] => 879
    [status] => y
    [award_status] => P
    [orderr] => 5
    [journal_id] => 1
    [googlesearch_link] => https://www.google.com/search?q=DYNAMICS+OF+MICROCIRCULATORY+CHANGES+IN+THE+RETINA+OF+PATIENTS+WITH+CHRONIC+KIDNEY+DISEASE+AFTER+KIDNEY+TRANSPLANTATION+Umida+F.+Mavlyanova%2C+Azamat+F.+Yusupov&rlz=1C1CHBD_enIN959IN959&sourceid=chrome&ie=UTF-8
    [edit_on] => 
    [is_status] => 1
    [journalname] => EPRA International Journal of Multidisciplinary Research (IJMR)
    [short_code] => IJMR
    [eissn] =>  2455-3662 (Online)
    [pissn] => - --
    [home_page_wrapper] => images/products_image/11.IJMR.png
)
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