This research paper presents an in-depth analysis of regional disparities in Karnataka, focusing on the construction of a Comprehensive Composite Development Index (CCDI) using data from 2020-21. By examining various socio-economic indicators such as literacy rates, per capita income, infrastructure development, and demographic factors, the study aims to identify the factors contributing to regional imbalances within the state. Through the categorization of districts into different development levels based on their relative progress, the research highlights the significant disparities that exist across various regions in Karnataka. The findings underscore the importance of targeted policy interventions and strategic measures to address these imbalances and promote inclusive growth and development across the state