This research aimed to assess heavy metals concentration, Electrical conductivity, and pH of River Wewe, Asafo-fittamu drainage, and Suame Magazine. The water samples were collected from Wewe, Asafo-fittamu, and Suame effluents at Kumasi in the Ashanti Region of Ghana in February. The samples were analyzed for Cu, Pb, Cr, and Cd, using Atomic Absorption Spectrometer (AAS). Electrical conductivity and pH were analyzed using electrical meter and pH meter respectively. The results of this study showed that there were signs that there were significant differences in concentrations of the metals in the effluents. The higher concentrations of heavy metals in the effluents may be due to the activities around such effluents. The mean concentration of heavy metals (mg/L) in the Asafo-fittamu effluents, 0.920 for copper, 0.945 for lead, 0.503 for chromium, and 0.101 for cadmium. The mean concentration of heavy metals (mg/L) in Suame Magazine effluents, 1.413 for copper, 1.141 for lead, 0.063 for chromium, and 0.093 for cadmium. Wewe river being the control study recorded mean concentrations (mg/L) of heavy metals, 0.442 for copper, 0.553 for lead, 0.051 for chromium, and 0.099 cadmium. pH means concentrations for Asafo-fittamu, Suame, and Wewe were 6.067, 6.173, and 6.586 respectively. Electrical conductivity means concentrations for Asafo-fittamu, Suame, and Wewe were 1673.333, 1623.333, and 390.000 respectively. Heavy metals concentration in Asafo-fittamu and Suame Magazine were significantly higher than that of the Wewe River. Care must be taken to reduce the number of pollutants released into the effluents to prevent the future increase in heavy metals concentration in the effluents so that its concentrations would not exceed the national and international standards