In almost all countries of the world, including Uzbekistan, the COVID-19 pandemic in 2020 has become a year of great trials for the World Health Organization and the health system of each country, continuing into 2021. In a short period of time, the COVID-19 pandemic, which has spread to almost all countries of the world, has proven that even the health care system of developed countries is not ready for such a complex process with its rapid spread and high mortality rates. The human factor was the main factor in the spread of the COVID-19 disease, and the role of natural and geographical factors was insignificant. That is, it became clear that the prevalence of this disease among the population is directly related to the strict observance of the established sanitary and hygienic rules by people.