In Ayurveda, datura is a well-known and commonly used medicine. Ayurveda recommends a series of steps called Shodhana (purification operations) in order to transform the seeds of this plant into a safe therapeutic medication because they are thought to be extremely hazardous. Datura, also known as Datura alba Linn in botanical terms, is one of the upavisha Vargas. Any upavisha group, such as the drug class datura, cannot be employed in treatment very efficiently unless it has through certain purifying procedures known as shodhana. To identify the chemically active principles, a comparative examination of the phytochemical components of the ashodita and goksheera shodhita datura beeja is conducted in the current study. To determine a plants active ingredient and determine whether it has therapeutic potential, the phytochemical analysis is very useful. The current study will analyse the phytochemical parameters in ashodita (unpurified) and shodhita datura beeja. After the evaluation, the extractive values of shodhita datura beeja as compared to the ashodita datura beeja are decreased. The extract from the samples of datura beeja was done for primary phytochemical analysis and was found to have less toxic chemical constituents compared to ashodita datura beeja and with safe and more therapeutic value.