This research paper provides a comprehensive review of the role of miasms in pathological cases. Miasms, a concept introduced by Samuel Hahnemann, the founder of homeopathy, refer to underlying predispositions or energetic imbalances that can lead to the manifestation of diseases. The paper explores the historical development of the miasmatic theory and its significance in understanding and treating pathological conditions. It examines the three primary miasms proposed by Hahnemann, namely Psora, Sycosis, and Syphilis, and their corresponding symptoms, manifestations, and treatment approaches. The paper also discusses the modern perspectives on miasms and their relevance in contemporary medical practice. Finally, it highlights the potential challenges and controversies associated with the concept of miasms and proposes areas for future research.