This article shows the social, political and economic situation of Mavorunnahr at the end of the 15th century and the beginning of the 16th century, the decline of the Timurid dynasty and the factors that caused Shaibani Khan to march to Mavorunnahr. Shaibani Khans founding of the state and the subsequent name of this state as the Bukhara Khanate, as well as the activities of the Shaibani rulers, are covered.