Age-related features of the course of combined inflammatory pathology of the rhino-orbital zone in 154 children were analyzed depending on the location and nature of the inflammatory process. The patients were observed by otorhinolaryngologists on an outpatient and inpatient basis. The study involved 154 (100%) children aged 0 to 17 years. Divided into 4 groups. In all children, depending on age, combinations of acute otitis with rhinitis, conjunctivitis and dacryocystitis, stenosis of the nasolacrimal duct, various forms of sinusitis were identified, with a tendency to increase depending on the age of the child.