Heavy metal pollution is a serious environmental problem. The presence of such metals in different areas of an ecosystem subsequently leads to the contamination of consumable products such as dietary and processed materials. Accurate monitoring of metal concentrations in various fish samples is of importance in order to minimize health hazards resulting from exposure to such toxic substances. For this purpose, it is essential to have a general understanding of the basic principles for different methods of elemental analysis. This article provides an overview of the most sensitive techniques of elemental analysis such as atomic absorption, ICP-OES mass spectrometry, Gas chromatography, and other techniques.