This study investigates the formulation of a cold cream enriched with pomegranate peel extract to assess its potential antibacterial and anticoagulant properties. Pomegranate peels, rich in bioactive compounds, were extracted using a solvent extraction method[1]. The obtained extract was incorporated into a cold cream base following standardized procedures. The formulated cream was then subjected to various analytical tests to evaluate its antibacterial efficacy against common pathogens and its ability to inhibit blood coagulation. Results demonstrated promising antibacterial activity against a spectrum of bacteria, including both Gram-positive and Gram-negative strains, suggesting its potential as a natural alternative to synthetic antimicrobials. Additionally, the cream exhibited significant anticoagulant properties, indicating its potential application in the management of thrombotic disorders[2]. This study underscores the feasibility of utilizing pomegranate peel extract in cold cream formulations for both therapeutic and cosmetic purposes, offering a natural and sustainable approach to skincare and healthcare. Further research is warranted to elucidate the mechanisms underlying these observed activities and optimize formulation parameters for enhanced efficacy and stability.