Bronchial asthma remains a pressing issue in pediatrics, with high prevalence and a continuous increase in morbidity among children. It has been found that most children with bronchial asthma have a history of perinatal central nervous system (CNS) damage. Despite progress in the diagnosis and treatment of bronchial asthma, the mechanisms by which perinatal CNS lesions influence asthma development are varied, and existing treatment regimens for such children are not always highly effective. This highlights the need for improved treatment methods for children with bronchial asthma who also suffer from the consequences of perinatal CNS injury.