White blood cells (WBCs), or leukocytes, play a crucial role in the body’s immune. System by defending against infections, foreign invaders, and abnormal cells. Disorders of white blood cells can arise from either excessive proliferation or deficiency of these cells, leading to a broad spectrum of diseases, including leukemias, lymphomas, and immune disorders. This review provides an overview of the most common disorders affecting white blood cells, focusing on the pathophysiology, clinical manifestations, diagnosis, and treatment options.Disorders Of White Blood Cells (WBCs) Disorders of white blood cells (WBCs), or leukocyte disorders, affect the production, function, or quantity of these immune cells, leading to significant health complications