Obesity is a growing global health problem, leading to serious conditions like numerous chronic diseases, including type 2 diabetes, cardiovascular disease, and certain cancers. While lifestyle changes like diet and exercise are important, many people need medication to help with weight loss. Currently, several drugs are approved for treating obesity, including GLP-1 receptor agonists (e.g. naltrexone-bupropion,) and combinations like phentermine-topiramate. These medications help with weight loss by reducing hunger, increasing feelings of fullness, and improving metabolism. New treatments are also being developed, such as drugs that target different hormones or gene-based therapies, offering hope for even more effective solutions. This review covers the current obesity drugs, how they work, and what new treatments might be available in the future