Calculation of molecular properties and bioactivity of the simple drug molecules like aspirin, paracetamol, and the drugs of your choices using the online server molinspiration. ABOUT MOLINSPIRATION; Molinspiration is a privately owned company focused on development and application of modern cheminformatics techniques, especially in connection with the web. Molinspiration was founded in 1986 as a spin-off of Bratislava University. ABOUT PASS STUDY: Post-authorisation safety studies (PASS) are essential in monitoring the safety and effectiveness of pharmaceutical products after they have been approved for public use. While pre-marketing clinical trials provide vital information on a drug’s efficacy and safety, they are often limited by sample size, duration, and patient population diversity. PASS are conducted to gather real-world data on the long-term safety and effectiveness of medicines once they are widely used. This review aims to explore the role of PASS in pharmacovigilance, including study designs, methodologies, regulatory requirements, and challenges associated with their implementation.