The genus Cordia contains a large number of trees and shrubs that are frequently found in warmer climates and have been used to treat a variety of illnesses. Numerous phytochemicals with varying activity, including as flavonoids, alkaloids, terpenes, tannins, and glycerides, were separated and tested from various C. Dichotoma sections. This plant has been shown to have several significant pharmacological qualities, such as hepatoprotective, antidiabetic, anti-inflammatory, anthelmintic, analgesic, anticancer, antioxidant, and antibacterial effects. C. Dichotoma is a promising natural antioxidant source with notable anti-inflammatory and therapeutic effects. We have covered the antioxidant potential of C. Dichotoma in brief in this review, which can be used as a guide for further studies on the plant’s potential health benefits.