Throat infections are a common ailment, ranging from mild sore throats to severe conditions like tonsillitis and pharyngitis, often caused by bacterial, viral, or fungal pathogens. Traditional medicine has long relied on herbal remedies for such conditions, with Zingiber officinale (ginger) being a cornerstone treatment for its potent bioactive compounds. Ginger contains a plethora of phytochemicals, such as gingerols, shogaols, and essential oils, which exhibit significant antimicrobial, anti-inflammatory, and analgesic effects. This review synthesizes traditional practices, experimental evidence, and modern applications of ginger for throat infections. Challenges such as the lack of standardization and quality control are discussed alongside prospects for developing ginger-based therapeutics.