Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood1. Wallerian degeneration is one of the major pathologies in spastic cerebral palsy. The cause of cerebral palsy (CP) and its effect on function vary from person to person. Wallerian degeneration is a series of cellular and molecular events that occur after a nerve is injured and the distal segment of an axon is separated from its cell body2. Cerebral palsy (CP) is the leading cause of childhood disability affecting function and development3. Population based studies around the world reports prevalence incident of CP ranging from 1.5 to 4 per 1000 live birth4. Cerebral palsy is caused by damaged or abnormal development in the parts of the brain that control movement, balance and posture5. Symptom of cerebral palsy can vary greatly, as it is a multi-factorial disease with clinical features of a wide variation, it cannot be correlated with any single disease or condition in Ayurveda. According to Vagabhatta, it can be classified in the disease categories of sahaja (hereditary) and garbhaja (congenital) type of diseases. It can be taken as Vata Vyadhi as far as its aetiology and symptomatology are concerned.