Background: - Due to the busy schedule in society no one is focusing to maintain their health, so most are affected with one or more diseases. The things that create trouble in most of the people are having faulty dietary habit & not following Dinacharya and Rutucharya. So different diseases related to daily life are rampantly appeared, out of them Amavata is one of the most common. Materials and Methods: -30 No. of Amavata patients were randomly selected from OPD, IPD of Govt. Ayurvedic College & Hospital, Balangir. A special proforma was prepared which includes details of history taking, physical sign and symptoms, subjective and objective parameters. Result and Discussion: - During the entire duration of therapy, there was not any adverse/untoward observed for both the trial groups. Here, Group A showed better result in overall total parameters. Conclusion: - The effect of the medicine, that is, Sunthyadi kwatha is more significant in Amavata than Panchakola churna in this study.