‘Kustha’ incuded all the skin disease which were described in Ayurveda, which are further divided into Maha Kustha & Kshudra Kustha. Vicharchika is one of the Kshudra Kustha runs a chronic course generally considered difficult to cure & even if it is cured, relapses are common; it is characterized with symptoms, namely Kandu (itching), Srava (discharge), Pidika (vesicles), and Shyava (discolouration) [1]. The clinical presentation of Vicharchika is similar to Eczema in modern dermatology. Eczema (also called as atopic dermatitis) is characterized by dry itchy skin with areas of poorly demarcated erythema and scale. In the acute phase, eczema may be vesicular and oozing, in the chronic phase it may become hyperpigmented and lichenified (thickened). Excoriations (scratch marks) are frequently seen. The modern science has greatly advanced, particularly in dermatology but there is no specific medicaments for sure cure of eczema but symptomatic treatments like anti allergic,steroids are used but they produce serious side effects like nephrotoxicity, osteoporosis, skin cancer etc. Ayurveda offers treatment for the root cause of eczema by cleansing vitiated Doshas and balancing the Doshas and Dhatus. Materials and Method: - This is a randomised open label clinical trial (single group). For this study patients of Vicharchika (Eczema) were selected randomly from the O.P.D. and I.P.D. of the Govt. Ayurvedic College and Hospital, Balangir. Observation and Results- It had been observed that 8(26.67%) patients were having marked improvement, 9(30%) were having Moderate improvement, 11(36.67%) were having mild improvement and 2 (6.67%) were having no improvement. Conclusion- Clinical study concludes that Khadira Triphaladi kasaya and Karanja Veeja Taila was effective in Vicharchika (Eczema) along with avoidance of Apathya Ahara Vihar.