This article focuses on the grammatical problems faced by translators when translating from Uzbek into English. Key grammatical differences between the two languages, such as word order, agglutination, use of articles, case forms and pluralization, are examined. The difficulties encountered in transferring Uzbek grammatical constructions into English are analyzed, as well as strategies that translators can use to achieve accuracy and preserve the meaning of the original. The article emphasizes the importance of paying close attention to the grammatical features of both languages for successful translation and comprehension of texts.