This study explores the critical aspects of transportation fleet and cargo management, focusing on optimizing logistics operations, improving fleet efficiency, and ensuring timely delivery of goods. The research examines the role of technology in modern fleet management, including the use of GPS tracking, telematics, and data analytics to monitor vehicle performance and cargo conditions. It also investigates strategies for route optimization, fuel management, vehicle maintenance, and compliance with safety and environmental regulations. Through case studies and industry data analysis, the study highlights best practices and challenges faced by logistics companies in managing diverse fleets and varying cargo types. The findings aim to support businesses in enhancing operational efficiency, reducing costs, and improving customer satisfaction in an increasingly competitive and dynamic transportation sector.