Postmenopause is a critical stage in a woman’s life marked by the cessation of menstruation and significant hormonal changes, primarily the decline in estrogen levels. These changes result in a variety of physical and psychological symptoms, including hot flashes, mood swings, vaginal dryness, osteoporosis, and sleep disturbances. This study focuses on the formulation and evaluation of medicated lozenges incorporating herbal agents such as Caraway (Carum carvi), Fenugreek (Trigonella foenum-graecum), and Coriander (Coriandrum sativum), known for their phytoestrogenic and therapeutic properties. Lozenges provide a convenient, palatable, and effective oral delivery system with potential for both local and systemic effects via buccal absorption. The prepared lozenges were evaluated for physicochemical parameters including hardness, friability, weight variation, disintegration time, drug content, and in vitro drug release. The results demonstrated that the herbal lozenges were pharmaceutically acceptable, stable, and potentially effective in alleviating postmenopausal symptoms. This study suggests that herbal lozenges could serve as a safe and user-friendly alternative for managing postmenopausal discomfort.