Aphthous Stomatis or mouth ulcer is the most common condition that we encounter clinically the lesions are single or multiple superficial and deep sealed and are associated with microbial invasions. Herbal gel formulated were stable, safe, and effective over to synthetic formulations for the treatment of mouth ulcer. Mouth ulcer often causes pain irritation of the sores salty, spicy, and sour food items and may cause discomfort while healing occurs due to use of chemical formulation. This project focused on the preparation of a herbal mouth ulcer healing gel because better cultural acceptability, better compatibility, with human body and less side effects. The gel was prepared by using alcoholic extract of Aloe barbadensis and Azadirachta indica leaves and extract powder of turmeric. Developed formulation were transparent, homogeneous and pH ranges from 6-8. Formulation showed acceptable rheological behaviour with applicable spreadability and Extrudability properties, however further clinical studies are required to established clinical efficacy of prepared herbal gels.