A transdermal patch is a medicated adhesive patch that you place on your skin to deliver medication directly into your bloodstream. This method is part of a newer way to deliverdrugs, which offers benefits over traditional methods like pills. Transdermal patches come in different sizes and can contain one or more active ingredients. This review providesimportant information about transdermal patches, including their advantages and disadvantages, how they work, the different types available, their basic components, methods of making them, how they are evaluated, and their uses. Many types ofmedications are now available in patch form.Transdermal patch technology offers a promising alternative for pain management by delivering drugs directly through the skin into systemic circulation. This method bypasses the gastrointestinal tract, reducing potential side effects and improving patient compliance. Among various analgesics, drugs like diclofenac sodium are effectively administered via transdermal patches, providing sustained and controlled release over extended periods. The patches ensure steady plasma drug levels, minimize dosing frequency, and are especially useful in chronic pain conditions such as arthritis and musculoskeletal disorders.