The transition from 1G to 5G has transformed the view of communication as fast, low latency, and very high-level connectivity. This paper reviews the implications of 5G on the Internet-of-Things (IoT) ecosystem based on its much-improved near real-time data transfer, ultra-reliable connectivity, and connectivity through all levels of devices. The possible uses of AI and LSTM for predictive analytics, anomaly detection, and ultimately autonomous decision making in the areas of health care, smart cities, Industry 4.0, and logistics are considered. There are many positives in addition to security and costs of infrastructure and computing. The potential for the future may include federated learning with LSTM, and continued development of 5G into a more intelligent, secure, and autonomous use of IoT applications.