The term "patches" refers to transdermal drug delivery systems (TDDS), which are dosage forms intended to apply a therapeutically effective quantity of medication to a patient's skin. To provide medicinal substances The entire morphological, biophysical, and physicochemical characteristics of the human skin must be taken into account for systemic impacts. By improving patient compliance and avoiding first pass metabolism, respectively, transdermal administration offers a significant advantage over injectables and oral methods. Transdermal delivery removes pulsed access into the systemic circulation and permits continuous injection of medications with brief biological half-lives in addition to providing controlled, continuous drug administration. This frequently results in unfavorable side effects. As a convenient resource for research scientists working on TDDS, the TDDS review papers offer important insights about transdermal drug delivery systems and its evaluation procedure. The pharmaceutical industry has become a trendier industry due to technological advancements.its assets. Convectional dose forms were used in the past, however new drug delivery systems are being used. Transdermal patches are among the most innovative new drug delivery technologies. The transdermal medication delivery system has the benefit of being a painless method of drug administration.