The current education system has moved towards multi-faceted thinking. There is a lot of diversity in the current education system, where there are different students based on economic status, caste, religion, etc. To meet the needs of all those students, teachers also have to be skilled in the same way. Currently, the use of artificial intelligence has increased greatly for the development of education. Therefore, teacher training curriculum should provide such content, that after studying it, future teachers are able to meet the needs of students in all aspects. This study conducted to revealed the challenges and opportunities related to AI-enhanced inclusive pedagogy in teacher training curriculum. This research has been conducted through the analysis of various secondary sources such as published research papers, articles, various policy documents and various literature, books etc. The findings suggest that various key challenges faced by teacher educators and trainees in integrating AI tools for inclusive teaching practices like- insufficient training opportunities, limited access of resources, lack of institutional support, lack of digital infrastructure etc. However, opportunities offered by AI- based technologies for enhancing teacher competency and inclusion skills like- availability of advance tech tools, flexible teaching learning system, enhanced collaboration and network, support for inclusive education etc. Therefore, in today’s 21st century education systems, teachers use a variety of technologies in the field of education and there must be knowledge about educational technology in the teacher education curriculum.