This study entitled coping with the challenges in teaching MAPEH subjects among the non-specialized teachers of District 4 in Laguna was conducted to specifically answer the following questions; What is the demographic profile of the Teachers in MAPEH in terms of; Age; Gender; Years in Service; Educational Attainment and Specialization? What is the coping mechanism of the Teachers in MAPEH in terms of: Time Management; Academic Advice and Mentoring; Appraisal Focused; Emotional-Focused; Occupation- focused coping? Do the coping mechanism used by teachers significantly affect the performance of non-specialized teachers teaching MAPEH of District 4 in Laguna? The study utilized a descriptive design to determine the coping mechanism of the non-specialized teachers in MAPEH. The main source data of this study was the survey questionnaire which was prepared by the researcher and statistically treated by the use of simple descriptive statistics such as frequency, percentage and the mean to determine the significant effect on the performance of the non-specialized teachers in MAPEH of the District of 4 in Laguna. In order to conduct this study, letters were sent to the Schools Divisions Superintendent Dr. Marites A. Ibanez, asking permission and approval to conduct the study, and to the School Principals of the selected schools, asking to distribute questionnaires to the ones teaching MAPEH. Preparation of self-made questionnaire by the researcher followed. The researcher-made questionnaire was checked by the thesis adviser. Face validation of the contents of the questionnaire was done by the adviser of the researcher and other persons with specialization in the field. They were vital members of the education team. Researchers use purposive sampling when they want to access a particular subset of people, as all participants of a study are selected because they fit a particular profile. Each individual was chosen entirely by chance and each member of the population had an equal chance of being included in the sample. The respondents of the study consisted of fifty non-major or non-specialized in MAPEH inn District 4 in Laguna. The purpose of the study may offer literature and findings that may be useful in the conduct of future studies more particularly in the context of communication considering the stressor and how to cope with the challenges of the teachers in teaching a non-major subject. Copies of the questionnaire were multiplied based on the number of the respondents. Then it was administered. With confidentiality, the gathered information was transferred in a tally sheet. Subsequently, codes were assigned to each indicator. The encoded data were given to the researcher’s statistician for the descriptive analysis. The gathered data were interpreted and presented in textual and tabular forms and appropriate interpretation was made. The methods used was statistical to analyze and interpret the data gathered, the weighted mean and the F-test formula which is the statistical test in which the test statistic has an F-distribution under the null hypothesis. It is most often used when comparing statistical models that have been fitted to a data set, in order to identify the model that best fits the population from which the data were sampled. The implication of this research is to find out the importance of how teachers of MAPEH especially the non-majors become aware of learning and dealing with teaching challenges. Have an important mechanism for handling situations related to MAPEH teaching. The result showed that the coping challenges in teaching MAPEH subjects had no significant effect on the performance of the non-specialize Teachers teaching MAPEH subjects of District 4 in Laguna, and therefore the hypothesis was also rejected.