Now a day, traditional medicines are used for the most types of diseases. In this study, Ethanolic extraction of Passiflora edulis sims extract is used for anthelmintic activity. This plant extract is also used in treating different types of diseases. Leaves of Passiflora edulis sins are dried, powdered and extracted with ethanol in Soxhlet extractor. Indian adult earthworms (Pherithema posthuman) are used to check the anthelmintic activity by using these extracts. Result shows that leave part is been taken less time for the death and paralysis of earthworm. This extract was screened for anthelmintic activity.