Agada tantra is one of the unique branches among the eight branches of Ayurveda which deals with different poisoning conditions, diagnosis, and treatment. In Ayurveda Garavisha(~artificial poison) is mentioned as a type of Visha(~poison) which is formed by the combination of two or more poisonous or non-poisonous substances, which slowly gets accumulated in the body and ultimately affects all parts of the body by vitiating all Dosha(~humor), Dhatu(~tissues), Mala(~waste products) and Srotas(~channels). Many ayurvedic formulations are mentioned for the treatment of Garavisha. Ajeya ghrita is one among them which is explained in Ashtanga Sangraha. It is a form of Ghrita Kalpa (~ghee preparation), the use of Ghrita (~poison) plays an important role in the management of Visha (~poison) condition. Ajeya ghrita is a formulation that has a combination of many herbs, in which most of the herbs possess Vishahara (~antipoison) property. The ingredients are easily accessible and have a simple method of preparation may encourage the physician to use this formulation in the management of Visha (~poison) condition. Hence an effort is made to review the Ajeya ghrita for Vishahara (~anti-poison) property.