SYNTHESIS OF A NOVEL SERIES OF SCHIFF'S BASES FROM PABA AND PHENYL HYDRAZINE AND EVALUATION OF THEIR ANTIOXIDANT ACTIVITY
Yalamanchili Praharsha, Sashmitha Samuel.B
Assistant Professor, Marri Laxman Reddy Institute of Pharmacy
Over the past decade, the synthesis of Schiffâ€™s bases has become one of the main areas of interest in synthetic chemistry. These compounds have gained much attention, owing to their potential role as anti-inflammatory, anthelmintic, analgesic, antibacterial and antifungal agents. Thus, in view of the significance and diverse therapeutic activities of Schiffâ€™s bases we have aimed at a simple and efficient procedure for their synthesis by the reaction of various aldehydes with PABA and phenyl hydrazine and also evaluation of their antibacterial activities. We have been successful in synthesizing various Schiffâ€™s bases and also these compounds have been proved to have effective anti-oxidant activity.
Keywords: Schiffâ€™s bases, PABA, Phenyl hydrazine, Aldehydes, Dioxan, Hydrogen peroxide, scavenging activity
Journal Name :
EPRA International Journal of Research & Development (IJRD)
Published on : 2021-09-29